Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of MMP-13 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  14nMAssay Description:Inhibition of MMP-12 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  14.3nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  286nMAssay Description:Inhibition of MMP-1 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  286nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of MMP-7 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed