Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118986(1-(5-Fluoro-2-methyl-benzoyl)-4-(4-methoxy-benzene...)
Affinity DataIC50:  2nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118986(1-(5-Fluoro-2-methyl-benzoyl)-4-(4-methoxy-benzene...)
Affinity DataIC50:  4nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118986(1-(5-Fluoro-2-methyl-benzoyl)-4-(4-methoxy-benzene...)
Affinity DataIC50:  55nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118986(1-(5-Fluoro-2-methyl-benzoyl)-4-(4-methoxy-benzene...)
Affinity DataIC50:  271nMAssay Description:Concentration required in vitro to inhibit TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed