Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  14nMAssay Description:Inhibition of P38alphaMAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibit of human Met proto-oncogene tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibit of human c-Jun N-terminal kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148709((5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed