Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard

Curated by ChEMBL

LigandBDBM50547195(CHEMBL4798158)Copy SMILESCopy InChI

Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPhospholipid hydroperoxide glutathione peroxidase(Homo sapiens)
Institute Of Mit And Harvard

Curated by ChEMBL

LigandBDBM50547195(CHEMBL4798158)Copy SMILESCopy InChI

Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI