Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 39 hits in this display
BDBM50170965(17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacy...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Ki: 12nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 60 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Ki: 12nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHOK1 cell membranes incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Ki: 12nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHOK1 cell membranes incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
BDBM50170965(17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacy...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Ki: 487nMAssay Description:Displacement of [3H]Ile5,6-deltorphin-2 from DOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
BDBM50170965(17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacy...)
BDBM50170965(17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacy...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50170965(17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacy...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50170965(17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacy...)
BDBM50170965(17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacy...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Ki: >1.00E+4nMAssay Description:Displacement of [3H]WIN-55,212-2 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Ki: >1.00E+4nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Acetylcholinesterase(Electrophorus electricus (Electric eel))University Of Innsbruck And Center For Molecular Biosciences Innsbruck-Cmbi
Curated by ChEMBL
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
IC50: 2.00E+6nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
EC50: 17nMAssay Description:Agonist activity at human MOR expressed in CHOK1 cells assessed as stimulation of cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
EC50: 17nMAssay Description:Agonist activity at human MOR expressed in CHOK1 cells assessed as stimulation of cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
EC50: 500nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
EC50: 1.60E+4nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
EC50: 4.00E+3nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
EC50: 1.60E+4nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
BDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
EC50: 160nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair