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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of human PI3KCalpha by non-radiometric ADP-Glo assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MCE
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Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of PI3Kalpha in presence of 10 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Inhibition of PI3Kalpha/p85alpha (unknown origin) using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay or high-throughput ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 11nM
Assay Description:
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
DNA-dependent protein kinase catalytic subunit
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of DNA-PK (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
DNA-dependent protein kinase catalytic subunit
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of human DNA-PK by non-radiometric ADP-Glo assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
University of California San Francisco
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
University of California San Francisco
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of PI3Kgamma in presence of 10 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Inhibition of PI3KC2alpha (unknown origin) expressed in HEK293 cells using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47nM
Assay Description:
Inhibition of human PI3KC2alpha by non-radiometric ADP-Glo assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 58nM
Assay Description:
Inhibition of PI3Kdelta in presence of 10 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 58nM
Assay Description:
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 64nM
Assay Description:
Inhibition of PI3KC2beta (unknown origin) expressed in HEK293 cells using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay o...
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 64nM
Assay Description:
Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assay
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human))
University of California San Francisco
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 350nM
Assay Description:
Biochemical assay using PI3Ks and diversification of tolyl quinazolinone series.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human))
University of California San Francisco
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 350nM
Assay Description:
Inhibition of PI3Kbeta in presence of 10 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
Curtin University
Curated by
ChEMBL
Ligand
BDBM81368
(PIK90)
Copy SMILES
Copy InChI
Affinity Data
IC50: 830nM
Assay Description:
Inhibition of full length human recombinant VPS34 (unknown origin) using phosphatidylinositol and gamma-32P-ATP incubated for 20 mins by TLC assay or...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI