Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataKi:  0.620nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataIC50:  431nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataIC50:  2.92E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50332283((R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed