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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Ligand
BDBM624562
((3-bromo-4-{[(7-methoxyquinolin-4- yl)oxy]methyl}p...)
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Affinity Data
Ki: 152nM
Assay Description:
Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Ligand
BDBM624562
((3-bromo-4-{[(7-methoxyquinolin-4- yl)oxy]methyl}p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.80E+4nM
Assay Description:
Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Ligand
BDBM624562
((3-bromo-4-{[(7-methoxyquinolin-4- yl)oxy]methyl}p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 505nM
Assay Description:
Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
(Homo sapiens (Human))
Volastra Therapeutics
US Patent
Ligand
BDBM624562
((3-bromo-4-{[(7-methoxyquinolin-4- yl)oxy]methyl}p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+5nM
Assay Description:
Assay 1: Test compounds were plated in a 3 dilution scheme in a 384 well plate. To 50 nL of test compound in DMSO was added 2.5 μL ENPP-1 ECD in...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI