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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50441344
(CHEMBL2431763 | US9611224, Example 10)
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Affinity Data
IC50: 104nM
Assay Description:
Inhibition of His-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 1 hr by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Baculoviral IAP repeat-containing protein 2
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM50441344
(CHEMBL2431763 | US9611224, Example 10)
Copy SMILES
Copy InChI
Affinity Data
IC50: 104nM
Assay Description:
The peptide AVPIAQKSEK-(ε-biotin)-OH (SEQ ID NO: 1) 1:2 TFA (Peptide A) was identified as a substrate for the TR-FRET assay by screening the 6× ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50441344
(CHEMBL2431763 | US9611224, Example 10)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.40E+4nM
Assay Description:
Inhibition of His-tagged XIAP BIR3 domain (241 to 356) (unknown origin) after 1 hr by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Baculoviral IAP repeat-containing protein 3
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM50441344
(CHEMBL2431763 | US9611224, Example 10)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.48E+4nM
Assay Description:
The peptide AVPIAQKSEK-(ε-biotin)-OH (SEQ ID NO: 1) 1:2 TFA (Peptide A) was identified as a substrate for the TR-FRET assay by screening the 6× ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI