Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

LigandBDBM50144749((S)-2-[((S)-1-Benzenesulfonyl-azetidine-2-carboxim...)Copy SMILESCopy InChI

Affinity DataIC50:  0.100nMAssay Description:Displacement of 125I-VCAM-Ig from VLA4 in human Jurkat cells incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50144749((S)-2-[((S)-1-Benzenesulfonyl-azetidine-2-carboxim...)Copy SMILESCopy InChI

Affinity DataIC50:  19nMAssay Description:Inhibitory activity of compound against alpha4-beta7 integrin using MAdCAM-Ig ligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI