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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Glycogen synthase kinase-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50219327
(GW811168X | PYRAZOLOPYRIMIDINE 2)
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Affinity Data
IC50: 2.5nM
Assay Description:
Inhibition of glycogen synthase kinase-3 (GSK3-beta)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
TBA
Ligand
BDBM50219327
(GW811168X | PYRAZOLOPYRIMIDINE 2)
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Copy InChI
Affinity Data
IC50: 2.5nM
Assay Description:
Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells using GS1 as substrate and [gamma32]ATP after 30 min by scinitllation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Glycogen synthase kinase-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50219327
(GW811168X | PYRAZOLOPYRIMIDINE 2)
Copy SMILES
Copy InChI
Affinity Data
EC50: 310nM
Assay Description:
Inhibition of glycogen synthesis in rat skeletal muscle L6 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI