Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50108216((S)-2-[((R)-3-Methanesulfonyl-thiazolidine-4-carbo...)Copy SMILESCopy InChI

Affinity DataIC50:  0.420nMAssay Description:Inhibition of integrin alpha4-beta1 of human Jurkat cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50108216((S)-2-[((R)-3-Methanesulfonyl-thiazolidine-4-carbo...)Copy SMILESCopy InChI

Affinity DataIC50:  13nMAssay Description:Inhibition of integrin alpha4-beta7 of human RPMI-8866 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI