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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
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Affinity Data
Ki: 10nM
Assay Description:
Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of DYRK1A (unknown origin) by TR FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of DYRK1B (unknown origin) by TR FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of DYRK2 (unknown origin) by ADP hunter plus assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: 65nM
Assay Description:
Inhibition of DYRK2 (unknown origin) by TR FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80E+3nM
Assay Description:
Inhibition of PIM1 (unknown origin) by ADP hunter plus assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 9
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
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Copy InChI
Affinity Data
IC50: 4.40E+3nM
Assay Description:
Inhibition of CDK9 (unknown origin) by TR FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of PAK4 (unknown origin) by ADP hunter plus assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
Vernalis (R&D)
Curated by
ChEMBL
Ligand
BDBM50581228
(CHEMBL5081341)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of Aurora A (unknown origin) by ADP hunter plus assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI