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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of PI3KC2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3KC2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Vps34More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed