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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast))
Nippon Roche Research Center
Ligand
BDBM50121720
((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)
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Affinity Data
IC50: 1nM
Assay Description:
Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
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Target
Glycylpeptide N-tetradecanoyltransferase 1/2
(Homo sapiens (Human))
Nippon Roche Research Center
Curated by
ChEMBL
Ligand
BDBM50121720
((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)
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Affinity Data
IC50: 1.30nM
Assay Description:
In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human))
Nippon Roche Research Center
Ligand
BDBM50121720
((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)
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Copy InChI
Affinity Data
IC50: 69nM
Assay Description:
Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Glycylpeptide N-tetradecanoyltransferase 1/2
(Homo sapiens (Human))
Nippon Roche Research Center
Curated by
ChEMBL
Ligand
BDBM50121720
((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)
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Copy InChI
Affinity Data
IC50: 3.00E+4nM
Assay Description:
In vitro inhibitory activity against Aspergillus fumigatus Nmt (AfNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycylpeptide N-tetradecanoyltransferase 1/2
(Homo sapiens (Human))
Nippon Roche Research Center
Curated by
ChEMBL
Ligand
BDBM50121720
((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.90E+4nM
Assay Description:
In vitro inhibitory activity against human Nmt (HsNmt) using 0.5 uM peptide GNAASAR-R-NH2 and 0.5 uM myristoyl-CoA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI