Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL

LigandBDBM50289958(CHEMBL2018592)Copy SMILESCopy InChI

Affinity DataEC50:  3.00E+3nMAssay Description:Activity at human CFTR delta F508 mutant expressed in forskolin-stimulated FRT cells assessed as increase in iodine influx measured as decrease in YF...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of California Davis

Curated by ChEMBL

LigandBDBM50289958(CHEMBL2018592)Copy SMILESCopy InChI

Affinity DataEC50:  3.02E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI