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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi:  567nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi:  2.47E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi:  4.12E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataKi: >5.03E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataIC50:  210nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201218((R)-2-(2,5-dioxoimidazolidin-4-yl)-N-(4-((2-methyl...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed