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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetStromelysin-1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208341(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi:  567nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208341(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208341(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi:  2.47E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208341(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi:  4.12E+3nMAssay Description:Binding affinity to MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208341(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi: >5.03E+3nMAssay Description:Binding affinity to MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208341(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataIC50:  439nMAssay Description:Inhibition of pTACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed