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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50204399
((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of pig TACE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50204399
((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
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Affinity Data
IC50: 130nM
Assay Description:
Inhibition of TACE in human whole blood
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50204399
((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
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Affinity Data
IC50: >2.00E+3nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50204399
((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
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Affinity Data
IC50: >2.00E+3nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50204399
((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50204399
((3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)met...)
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Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI