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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
59
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Ki: 7.70nM
Assay Description:
Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Ki: 29nM
Assay Description:
Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Ki: 38nM
Assay Description:
Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from human GPR40 expressed in CHO cells a...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Ki: 38nM
Assay Description:
Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from human GPR40 expressed in CHO membrane...
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Target
Free fatty acid receptor 1
(Rattus norvegicus)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Ki: 140nM
Assay Description:
Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from rat GPR40 expressed in CHO cells aft...
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Free fatty acid receptor 1
(Rattus norvegicus)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Ki: 140nM
Assay Description:
Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from rat GPR40 expressed in CHO membranes ...
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Target
Sodium/bile acid cotransporter
(Homo sapiens (Human))
Southwest Jiaotong University
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of NTCP in human hepatocytes
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Target
Solute carrier organic anion transporter family member 1B1
(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by
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BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
IC50: 2.28E+3nM
Assay Description:
Inhibition of human OATP1BA
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Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Chinese Academy Of Sciences
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BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
IC50: 2.41E+3nM
Assay Description:
Inhibition of human MRP2
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Target
Solute carrier organic anion transporter family member 1B3
(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
IC50: 1.12E+4nM
Assay Description:
Inhibition of human OATP1B3
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Target
Melanocortin receptor 4
(Rattus norvegicus)
Cadila Healthcare
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 2.70E+4nM
Assay Description:
Agonist activity at GPR40 in rat RINm cells assessed as increase glucose-stimulated insulin secretion after 1 hr by ELISA
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 1.90nM
Assay Description:
Agonist activity at human GPR40 expressed in HEK293 cells measured after 18 to 20 hrs by beta-gal based luciferase reporter gene assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 14.1nM
Assay Description:
Agonist activity at human FFA1 receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescence spectrophotometry
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Target
Free fatty acid receptor 1
(Rattus norvegicus)
Takeda Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 93nM
Assay Description:
Agonist activity at GPR40 in rat INS-1 cells assessed as glucose-stimulated insulin secretion
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 42nM
Assay Description:
Agonist activity at human GPR40 transfected in CHO cells by calcium flux assay
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Target
Free fatty acid receptor 4
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human GPR120 expressed in CHO cells assessed as calcium influx after 30 mins by FLIPR assay
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Target
Free fatty acid receptor 2
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human GPR43 expressed in 293 cells assessed as cAMP accumulation after 30 mins by Alphascreen method
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Free fatty acid receptor 3
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human GPR41 expressed in 293 cells assessed as cAMP accumulation after 30 mins by Alphascreen method
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Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 14nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells assessed as calcium influx by FLIPR assay in presence of 0.1 % BSA
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 16nM
Assay Description:
Agonist activity at human GP40 receptor expressed in CHO cells assessed as increase in intracellular calcium level for 90 secs by FLIPR assay in the ...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 27nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo 4-AM dye based assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 34nM
Assay Description:
Agonist activity at human FFAR1 expressed in CHO cells assessed as increase in intracellular calcium level by Fluo 4-AM dye-based FLIPR assay
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Target
Free fatty acid receptor 4
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human FFAR4 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by luminescence assay
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Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 14nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells after 24 hrs by NFAT-luciferase reporter gene assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 33nM
Assay Description:
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium levels measured for 90 secs by Fluo 4-AM...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 5.10E+3nM
Assay Description:
Transactivation of human GPR40 expressed in HEK293 cells after 24 hrs by Elk-Gal4 luciferase reporter assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 32nM
Assay Description:
Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 39nM
Assay Description:
Agonist activity at recombinant human GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium flux measured for 120 secs by cal...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 80nM
Assay Description:
Agonist activity at human GPR40 expressed in human HEK293 cells assessed as increase in intracellular calcium flux after 10 mins by fluorescence assa...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 14nM
Assay Description:
Agonist activity at FFA1 (unknown origin)
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 45nM
Assay Description:
Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ flux after 1 hr by Fluo4-AM dye based FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 31nM
Assay Description:
Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assay
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Target
Melanocortin receptor 4
(Rattus norvegicus)
Cadila Healthcare
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 39nM
Assay Description:
Agonist activity at rat GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 37nM
Assay Description:
Agonist activity at FFA1 receptor (unknown origin) stably expressed in CHO cells assessed as increase in calcium flux by Fluo4-AM based FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 80nM
Assay Description:
Agonist activity at human FFA1 receptor expressed in HEK293 cells assessed as increase in intracellular Ca2+ flux by Fluo-4 dye based assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 45nM
Assay Description:
Agonist activity at human FFA1 receptor expressed in CHO cells by Fluo 4-AM dye based FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 53nM
Assay Description:
Agonist activity at GPR40 (unknown origin)
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 160nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 12nM
Assay Description:
Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...
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Target
Free fatty acid receptor 1
(Mus musculus)
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 8.60nM
Assay Description:
Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...
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Target
Melanocortin receptor 4
(Rattus norvegicus)
Cadila Healthcare
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 36nM
Assay Description:
Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 0.350nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Kd: 4.5nM
Assay Description:
Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: >1.00E+3nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
Kd: 12nM
Assay Description:
Binding affinity to human GPR40 expressed in CHO cells by LC-MS analysis
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 53nM
Assay Description:
Agonist activity at FFAR1 (unknown origin)
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 45nM
Assay Description:
Agonist activity at human FFA1 expressed in CHO cells measured by FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 7.70nM
Assay Description:
Agonist activity at FFAR1 (unknown origin)
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 26nM
Assay Description:
Agonist activity at human GPR40 expressed in Flp-InTM T-RexTM HEK293 cells assessed as stimulation of calcium mobilization
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 21.9nM
Assay Description:
Agonist activity at human GPR40 expressed in Flp-InTM T-RexTM HEK293 cells assessed as stimulation of calcium mobilization
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 25.7nM
Assay Description:
Agonist activity at human GPR40 expressed in Flp-InTM T-RexTM HEK293 cells assessed as stimulation of calcium mobilization in presence of 0.05% BSA
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Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
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Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 58nM
Assay Description:
Agonist activity at FFA1 receptor (unknown origin) expressed in human 132N1 cells measured for 90 secs by Fura-2 AM dye based calcium mobilization as...
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Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
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Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 9.30nM
Assay Description:
Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 28nM
Assay Description:
Agonist activity at human GPR40 expressed in CHO cells by FLIPR calcium flux assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 30nM
Assay Description:
Agonist activity at human FFA1 expressed in CHO cells assessed as intracellular Ca2+ level measured for 90 secs by Fluo-4 AM-based FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 30nM
Assay Description:
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by FLIPR assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 37.1nM
Assay Description:
hGPR40-CHO stably transfected cells were seeded into a 96-well plate at a density of 3×104/well, and incubated overnight in a 37° C., 5% CO2 cell inc...
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
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Affinity Data
EC50: 39nM
Assay Description:
Agonist activity at human FFA1 expressed in CHO cells assessed as increase in intracellular Ca2+ concentration by Fluo-4 AM based fluorescence assay
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50386790
(CHEMBL1829174 | CHEMBL2047159 | TAK-875 | US119052...)
Copy SMILES
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Affinity Data
EC50: 30nM
Assay Description:
Agonist activity at human FFA1 expressed in CHO cells assessed as induction of receptor activation by measuring Ca2+influx incubated for by FLIPR met...
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