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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataKi:  0.770nMAssay Description:Competitive inhibition of TTK (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of TTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged and sumo-tagged human TTK (1 to 275 residues) expressed in Escherichia coli pre-incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged Aurora A expressed in Sf21 cells by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human His-tagged Aurora B/full length recombinant human N-terminal GST-tagged INCENP (821-end residues) expressed in baculo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50183019(CHEMBL3819210)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human PLK4 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed