Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50167620((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)Copy SMILESCopy InChI

Affinity DataIC50:  2.10nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50167620((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)Copy SMILESCopy InChI

Affinity DataIC50:  6.20nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50167620((2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzene...)Copy SMILESCopy InChI

Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI