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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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Article
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
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Affinity Data
IC50: 4.70E+3nM
Assay Description:
Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MK2 (46 to 400) as substrate assessed as inhibition of phosphorylation after 60...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
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Affinity Data
IC50: 5.36E+3nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC sid
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In Depth
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PCBioAssay
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of p38-alpha (unknown origin) by p38alpha-MBP IoC assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of human recombinant MMP13 using Mca-Pro-cyclohexyl-Ala-Gly-Nva-His-Ala-Dap(Dnp)-NH2 substrate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20E+4nM
Assay Description:
Inhibition of human recombinant 5'-c-myc, His6-tagged p38-alpha using MSK1 as substrate assessed as inhibition of phosphorylation after 60 mins by EL...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
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Affinity Data
IC50: 5.01E+4nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Signal transducer and activator of transcription 1-alpha/beta
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.57E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM46421
(4-(4-methylphenoxy)-N-(4-pyridinylmethyl)benzeneca...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of MMP12
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI