Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50402991(CHEMBL2207428)Copy SMILESCopy InChI

Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein-tyrosine kinase 2-beta(Mus musculus)
Pfizer

Curated by ChEMBL

LigandBDBM50402991(CHEMBL2207428)Copy SMILESCopy InChI

Affinity DataIC50:  7.66E+3nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI