Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320411(CHEMBL1084209 | N-hydroxy-4-(4-(4-p-tolylpiperazin...)Copy SMILESCopy InChI

Affinity DataIC50:  1.90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320411(CHEMBL1084209 | N-hydroxy-4-(4-(4-p-tolylpiperazin...)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320411(CHEMBL1084209 | N-hydroxy-4-(4-(4-p-tolylpiperazin...)Copy SMILESCopy InChI

Affinity DataIC50:  682nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50320411(CHEMBL1084209 | N-hydroxy-4-(4-(4-p-tolylpiperazin...)Copy SMILESCopy InChI

Affinity DataIC50:  8.22E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI