Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetShort transient receptor potential channel 3(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

LigandBDBM50519470(CHEMBL4460029)Copy SMILESCopy InChI

Affinity DataIC50:  720nMAssay Description:Inhibition of YFP-tagged TRPC3 (unknown origin) expressed in HEK293 cells assessed as reduction carbhocol-induced receptor operated Calcium influx af...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails ArticlePubMed
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TargetCalcium release-activated calcium channel protein 1(Rattus norvegicus)
University Of Nebraska Medical Center

Curated by ChEMBL

LigandBDBM50519470(CHEMBL4460029)Copy SMILESCopy InChI

Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of ORAI/STIM1 in thapsigargin treated rat RBL2H3 cells assessed as reduction in store-operated calcium entry after 5 mins by fura-2-AM dye...More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseMCE
PC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI