Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50346919(CHEMBL1795685)Copy SMILESCopy InChI

Affinity DataKi:  17nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50346919(CHEMBL1795685)Copy SMILESCopy InChI

Affinity DataIC50:  38nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50346919(CHEMBL1795685)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI