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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311913(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Affinity DataIC50:  245nMAssay Description:Inhibition of Tel-fused KDR expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311913(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Affinity DataIC50:  275nMAssay Description:Inhibition of Tel-fused LCK expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311913(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Affinity DataIC50:  468nMAssay Description:Inhibition of Tel-fused LYN expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311913(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of Tel-fused InsR expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311913(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of Tel-fused SRC expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311913(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50311913(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed