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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50311913
(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
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Affinity Data
IC50: 245nM
Assay Description:
Inhibition of Tel-fused KDR expressed in mouse BAF3 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50311913
(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
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Copy InChI
Affinity Data
IC50: 275nM
Assay Description:
Inhibition of Tel-fused LCK expressed in mouse BAF3 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50311913
(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 468nM
Assay Description:
Inhibition of Tel-fused LYN expressed in mouse BAF3 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Insulin receptor
(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50311913
(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
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Affinity Data
IC50: 1.09E+3nM
Assay Description:
Inhibition of Tel-fused InsR expressed in mouse BAF3 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50311913
(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
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Affinity Data
IC50: 1.22E+3nM
Assay Description:
Inhibition of Tel-fused SRC expressed in mouse BAF3 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50311913
(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.37E+3nM
Assay Description:
Inhibition of LCK
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase HCK
(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50311913
(3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Inhibition of HCK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI