Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

LigandBDBM50305666(6-methyl-1H-indole-2-carboxylic acid | CHEMBL59600...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Ability to displace radioligand [3H]N-0437 from human dopamine D2 receptor transfected chinese hamster ovary cell membranes.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50305666(6-methyl-1H-indole-2-carboxylic acid | CHEMBL59600...)Copy SMILESCopy InChI

Affinity DataIC50:  6.30E+5nMAssay Description:Inhibition of 8His-tagged Pin1 PPIase domain (45-163)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedMMDB
PDB3D Structure (crystal)
Copy BDB DOI