Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL

LigandBDBM50428944(CHEMBL2333170)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Inhibition of human VCAM1 binding to integrin alpha4beta1 receptor in human Ramos cells labeled with Calcein AMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL

LigandBDBM50428944(CHEMBL2333170)Copy SMILESCopy InChI

Affinity DataIC50:  58nMAssay Description:Inhibition of human MAdCAM1 binding to integrin alpha4beta7 receptor in human RPMI 8866 cells labeled with Calcein AMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI