Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)Copy SMILESCopy InChI

Affinity DataIC50:  140nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI