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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50:  62nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50:  131nMAssay Description:Antagonist activity at human alpha4beta1integrin in human Jurkat cells assessed as reduction of VCAM-1-induced ERK1/2 phosphorylation after 60 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50:  343nMAssay Description:Inhibition of human alpha4beta7 integrin expressed in human RPMI8866 cells assessed as inhibition of cell adhesion to MadCam1More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha5beta3 integrin expressed in human SK-MEL-24 cells assessed as inhibition of cell adhesion to fibronectinMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50498364(CHEMBL3590533)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human alpha5beta1 integrin expressed in human K-562 cells assessed as inhibition of cell adhesion to fibronectinMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed