Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.00E+3nM
Assay Description:
MMP-8: 90 μL (29 ng) of human MMP-8 (Calbiochem #444229) was mixed with 10 μL of 10 mM APMA, and activated by reacting at 37° C. for 1 hour...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20E+4nM
Assay Description:
MMP-14: 90 μL (1.9 ng) of human MMP-14 (Calbiochem #475935) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.10E+4nM
Assay Description:
MMP-2: 90 μL (5 ng) of human MMP-2 (Calbiochem #444213) was mixed with 10 μL of 10 mM APMA, and activated by reacting at 37° C. for 1 hour....
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.90E+4nM
Assay Description:
MMP-3: 90 μL (1.5 ng) of human MMP-3 (Calbiochem #444217) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Matrix metalloproteinase-17
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.50E+4nM
Assay Description:
MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.70E+4nM
Assay Description:
MMP-9: 90 μL (11 ng) of human MMP-9 (Calbiochem #444231) was mixed with 10 μL of 10 mM APMA, and activated by reacting at 37° C. for 2 hour...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
MMP-13: 90 μL (18 ng) of human MMP-13 (Calbiochem # CC068) or 90 μL (130 ng) of human MMP-13 (Calbiochem #444287) was mixed with 10 μL...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Kaken Pharmaceutical
US Patent
Ligand
BDBM400703
(US10000476, Compound I-62)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
MMP-1: 180 μL (100 ng) of human MMP-1 (Calbiochem #444208) was mixed with 20 μL of 10 mM p-amino phenyl mercuric acetate (APMA), and activa...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI