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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human))
Eicosis
US Patent
Ligand
BDBM408986
(US10377744, Compound No. 7 | US11123311, Compound ...)
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Affinity Data
Ki: 0.260nM
Assay Description:
FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Epoxide hydrolase 1
(Homo sapiens (Human))
The Regents of The University of California
US Patent
Ligand
BDBM408986
(US10377744, Compound No. 7 | US11123311, Compound ...)
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Affinity Data
Ki: 0.260nM
Assay Description:
Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human))
Eicosis
US Patent
Ligand
BDBM408986
(US10377744, Compound No. 7 | US11123311, Compound ...)
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Copy InChI
Affinity Data
Ki: 0.260nM
Assay Description:
Inhibition of recombinant human sEH expressed in baculovirus expression system assessed as reduction in ACPU binding incubated for 1 hr by FRET displ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human))
Eicosis
US Patent
Ligand
BDBM408986
(US10377744, Compound No. 7 | US11123311, Compound ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.260nM
Assay Description:
Any of a number of standard assays for determining epoxide hydrolase activity can be used to determine inhibition of sEH. For example, suitable assay...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI