Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 11 hits in this display
IC50: 5.00E+3nMAssay Description:Inhibition of KDM4E (unknown origin) preincubated for 15 mins followed by histone substrate addition measured after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
IC50: 5.00E+3nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated for 15 mins followed by histone substrate addition measured after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
IC50: 3.40E+4nMAssay Description:Inhibition of KDM2A (unknown origin) preincubated for 15 mins followed by histone substrate addition measured after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
IC50: 9.60E+4nMAssay Description:Inhibition of PHD2 (unknown origin) preincubated for 15 mins followed by histone substrate addition measured after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
IC50: 1.06E+5nMAssay Description:Inhibition of KDM6B (unknown origin) preincubated for 15 mins followed by histone substrate addition measured after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
IC50: 1.78E+5nMAssay Description:Inhibition of KDM5C (unknown origin) preincubated for 15 mins followed by histone substrate addition measured after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
IC50: 1.91E+5nMAssay Description:Inhibition of KDM3A (unknown origin) preincubated for 15 mins followed by histone substrate addition measured after 1 hr by alphascreen assayMore data for this Ligand-Target Pair
EC50: 1.20E+4nMAssay Description:Inhibition of KDM4A in human MCF7 cells assessed as increase in H3K9me3 level after 24 hrs by DAPI staining based immunofuorescence assayMore data for this Ligand-Target Pair