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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Thymidine kinase 2, mitochondrial
(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
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Affinity Data
Ki: 500nM
Assay Description:
Inhibition of TK2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 180nM
Assay Description:
Inhibitory activity against HSV-1 Thymidine kinase in OST-TK-/HSV-1 TK+ cell line in combination with gancicclovir
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibitory effect against phosphorylation of [methyl-3H]dThd by Thymidine Kinase 2 (TK-2)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibitory concentration of the compound on phosphorylation of [methyl-3H]-dTh by HSV-1 Thymidine Kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase 2, mitochondrial
(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of thymidine kinase 2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase 2, mitochondrial
(Homo sapiens (Human))
Instituto De QuíMica MéDica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of [3H]methyl dThd phosphorylation by TK2
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20E+3nM
Assay Description:
Inhibitory activity against HSV-1 Thymidine kinase in OST-TK-/HSV-1 TK+ cell line in combination with BVAraU
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Deoxynucleoside kinase
(Drosophila melanogaster)
Instituto De QuíMica MéDica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.30E+3nM
Assay Description:
Inhibition of [3H]methyl dThd phosphorylation by Drosophila melanogaster dNK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.70E+3nM
Assay Description:
Inhibitory concentration against HSV-1 TK (WT) catalyzed [3H]-GCV phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.50E+4nM
Assay Description:
Inhibitory concentration of the compound on phosphorylation of [methyl-3H]-dTh by HSV-1 Thymidine Kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.50E+4nM
Assay Description:
Compound was evaluated for inhibitory effect against phosphorylation of [methyl-3H]dThd by HSV-1 Thymidine kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase
(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Instituto De QuíMica MéDica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.50E+4nM
Assay Description:
Inhibition of [3H]methyl dThd phosphorylation by HSV1 TK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibitory concentration against HSV-1 TK (A167Y) catalyzed [3H]-GCV phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thymidine kinase, cytosolic
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)
Curated by
ChEMBL
Ligand
BDBM50118490
(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+5nM
Assay Description:
Inhibitory concentration of the compound on phosphorylation of [methyl-3H]-dTh by human Thymidine Kinase 2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI