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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Fatty acid synthase
(Homo sapiens (Human))
3-V Biosciences
US Patent
Ligand
BDBM244405
(US10226449, cpd 14 | US9428502, 14)
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Affinity Data
IC50: 27nM
T: 2°C
Assay Description:
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Fatty acid synthase
(Homo sapiens (Human))
3-V Biosciences
US Patent
Ligand
BDBM244405
(US10226449, cpd 14 | US9428502, 14)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Genome polyprotein
(Hepatitis C Virus (Virus))
3-V Biosciences
US Patent
Ligand
BDBM244405
(US10226449, cpd 14 | US9428502, 14)
Copy SMILES
Copy InChI
Affinity Data
EC50: 31nM
Assay Description:
The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI