Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50:  3nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50:  10nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50:  10nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50:  40nMAssay Description:Inhibition of CLK (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50:  40nMAssay Description:Inhibition of DYRK1A expressed in human U2OS cells assessed as reduction in autophosphorylation at S520 residue incubated for 5 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DYRK2 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581214(CHEMBL5078833)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK9 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed