Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetEgl nine homolog 1(Homo sapiens (Human))
Akebia Therapeutics

US Patent

LigandBDBM618993(US20230295110, Compound 25.)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Akebia Therapeutics

US Patent

LigandBDBM618993(US20230295110, Compound 25.)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Akebia Therapeutics

US Patent

LigandBDBM618993(US20230295110, Compound 25.)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI