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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Egl nine homolog 1
(Homo sapiens (Human))
Akebia Therapeutics
US Patent
Ligand
BDBM619005
(US20230295110, Compound 37.)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Prolyl hydroxylase EGLN3
(Homo sapiens (Human))
Akebia Therapeutics
US Patent
Ligand
BDBM619005
(US20230295110, Compound 37.)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Prolyl hydroxylase EGLN2
(Homo sapiens (Human))
Akebia Therapeutics
US Patent
Ligand
BDBM619005
(US20230295110, Compound 37.)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
Time-resolved fluorescence resonance energy transfer (TR-FRET) assay was utilized to determine the enzymatic half maximal inhibitory concentration (I...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI