Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 12 hits in this display
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
IC50: 12nMAssay Description:Inhibition of PI3Kbeta in human PC3 cells assessed as suppression of AKT phosphorylation at Ser473 after 60 mins by ELISAMore data for this Ligand-Target Pair
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
IC50: 17nMAssay Description:Inhibition of PI3Kbeta in human PC3 cells assessed as suppression of AKT phosphorylation at Thr308 after 60 mins by ELISAMore data for this Ligand-Target Pair
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
Kd: 5.13E+3nMAssay Description:Binding affinity to human PI3Kalpha (108 to 1068 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
Kd: >3.02E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
Kd: 5nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
Kd: 955nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
Kd: >3.02E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
BDBM50200974(CHEMBL3975628 | US10087187, Compound 6)
Kd: 1.14E+4nMAssay Description:Binding affinity to human PI3Kgamma (144 to 1102 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair