Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent

LigandBDBM644699(US11866450, Compound 112)Copy SMILESCopy InChI

Affinity DataEC50: <1.00E+3nMAssay Description:Bath 1 Buffer consisted of 1 mM MgCl2, 160 mM NaCl, 4.5 mM KCl, 10 mM HEPES, 10 mM Glucose, 2 mM CaCl2).Chloride Free Buffer consisted of 1 mM Magnes...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent

LigandBDBM644607(Preparation of 20,20,22-trimethyl-4-(3-{2-[1-(trif...)Copy SMILESCopy InChI

Affinity DataEC50:  2.00E+3nMAssay Description:Bath 1 Buffer consisted of 1 mM MgCl2, 160 mM NaCl, 4.5 mM KCl, 10 mM HEPES, 10 mM Glucose, 2 mM CaCl2).Chloride Free Buffer consisted of 1 mM Magnes...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI