Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetHuntingtin(Homo sapiens (Human))
Columbia University

Curated by ChEMBL

LigandBDBM50097114(6-chloro-N-(4-chlorophenethyl)quinazolin-4-amine |...)Copy SMILESCopy InChI

Affinity DataIC50:  3.44E+3nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL

LigandBDBM50097114(6-chloro-N-(4-chlorophenethyl)quinazolin-4-amine |...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI