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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50401091
(CHEMBL2204436 | CHEMBL2385894)
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Affinity Data
IC50: 190nM
Assay Description:
Negative allosteric modulation of human mGlu3 expressed in AV-12 cells in presence of glutamate EC90 concentration by FLIPR assay
More data for this Ligand-Target Pair
Target Info
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Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50401091
(CHEMBL2204436 | CHEMBL2385894)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20E+3nM
Assay Description:
Negative allosteric modulation of human mGlu3 receptor assessed as Ca2+ flux by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50401091
(CHEMBL2204436 | CHEMBL2385894)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20E+3nM
Assay Description:
Negative allosteric modulation of mGlu3 assessed as thaillium flux through GIRK channels by cell-based assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50401091
(CHEMBL2204436 | CHEMBL2385894)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.25E+4nM
Assay Description:
Negative allosteric modulation of human mGlu2 expressed in AV-12 cells in presence of glutamate EC90 concentration by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50401091
(CHEMBL2204436 | CHEMBL2385894)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+4nM
Assay Description:
Negative allosteric modulation of mGlu2 assessed as thaillium flux through GIRK channels by cell-based assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50401091
(CHEMBL2204436 | CHEMBL2385894)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+4nM
Assay Description:
Negative allosteric modulation of human mGlu2 receptor assessed as Ca2+ flux by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI