Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Thermolysin
(Bacillus thermoproteolyticus)
University Of Troms£
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.25E+3nM
Assay Description:
Inhibition of Bacillus thermoproteolyticus thermolysin after 15 mins by microplate fluorescence analysis in presence of 0.5 to 2 mM substrate FaGLa
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A1
(Rattus norvegicus (rat))
North-West University
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H]DPCPX from Sprague-Dawley rat whole brain membrane A1AR by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
North-West University
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: 54nM
Assay Description:
Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Inhibition of TNKS1 (unknown origin) by fluorescence analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
Inhibition of TNKS2 (unknown origin) by fluorescence analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: 485nM
Assay Description:
Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thermolysin
(Bacillus thermoproteolyticus)
University Of Troms£
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.25E+3nM
Assay Description:
Inhibition of Bacillus thermoproteolyticus thermolysin after 15 mins by microplate fluorescence analysis in presence of 0.1 M substrate FaGLa
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.60E+3nM
Assay Description:
Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-glucuronidase
(Homo sapiens (Human))
University Of Karachi
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.98E+4nM
Assay Description:
Inhibition of beta-glucuronidase activity (unknown origin) assessed as p-nitrophenol formation after 30 mins using p-nitrophenyl-beta-D-glucuronide a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50321122
(2-Ethylquinazolin-4(3H)-one | CHEMBL1163173)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI