Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetHistone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50607590(CHEMBL5220332)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50607590(CHEMBL5220332)Copy SMILESCopy InChI

Affinity DataEC50:  200nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI