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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
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Affinity Data
Ki: 2nM
Assay Description:
Binding affinity to KDM5B (unknown origin)
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Article
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PDB
3D Structure (crystal)
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Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Binding affinity to KDM4A (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of human KDM5B using H3(1-21)K4-Me3-GGK Biotin as substrate and measured by Alphascreen assay
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
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CHEMBL
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PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of KDM6B (unknown origin) using biotin-H3K27me3 (21 to 44 residues) as substrate preincubated for 15 mins followed by substrate addition m...
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Target Info
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CHEMBL
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
IC50: 31nM
Assay Description:
Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
IC50: 31nM
Assay Description:
Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus-infected Sf9 cells using ARTKQTARK(Me3)STGGK...
More data for this Ligand-Target Pair
Target Info
PDB
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PubMed
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Target
Lysine-specific demethylase 5C
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
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Affinity Data
IC50: 65nM
Assay Description:
Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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CHEMBL
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Article
PubMed
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Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
IC50: 102nM
Assay Description:
Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Lysine-specific demethylase 3A
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
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Affinity Data
IC50: 5.30E+3nM
Assay Description:
Inhibition of KDM3A (unknown origin) using biotin-H3K9me2 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate addition mea...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Lysine-specific demethylase 2A
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
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Affinity Data
IC50: 1.29E+4nM
Assay Description:
Inhibition of KDM2A (unknown origin) using biotin-H3K36me2 (28 to 48 residues) as substrate preincubated for 15 mins followed by substrate addition m...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific demethylase 4A
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.50E+3nM
Assay Description:
Inhibition of FLAG tagged full length wild type human KDM4A transfected in HeLa cells assessed as decrease in demethylation of H3K9Me3 measured after...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.42E+4nM
Assay Description:
Inhibition of full length human wild type KDM5B transfected in HeLa cells assessed as decrease in demethylation of H3K4Me3 measured after 24 hrs by c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 5B
(Homo sapiens (Human))
Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
EC50: 600nM
Assay Description:
Binding affinity to recombinant human N-terminal KDM5B (26 to 772 residues) fused with ePL-tagged C-terminal transfected in HEK293T cells measured af...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Lysine-specific demethylase 4B
(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by
ChEMBL
Ligand
BDBM50151923
(CHEMBL3774537)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.00E+3nM
Assay Description:
Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI