Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 14 hits in this display
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
ADAMTS5(Rattus norvegicus (Rat))Galapagos
US Patent
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
IC50: 41nMAssay Description:Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assayMore data for this Ligand-Target Pair
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
IC50: 137nMAssay Description:Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in presence of 2% HSA by biochemical assayMore data for this Ligand-Target Pair
BDBM379555(US9926281, Compound 34)
IC50: 155nMAssay Description:Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 in absence of serum by biochemical assayMore data for this Ligand-Target Pair
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)
BDBM379555(US9926281, Compound 34)