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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50457829
(CHEMBL4208510)
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Affinity Data
IC50: 6.60nM
Assay Description:
Antagonist activity at prolink-tagged TrkB in human U2OS cells assessed as inhibition of BDNF-induced receptor phosphorylation by measuring reduction...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
NT-3 growth factor receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50457829
(CHEMBL4208510)
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Copy InChI
Affinity Data
IC50: 8.40nM
Assay Description:
Antagonist activity at prolink-tagged TrkC in human U2OS cells assessed as inhibition of NT3-induced receptor phosphorylation by measuring reduction ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50457829
(CHEMBL4208510)
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Affinity Data
IC50: 20nM
Assay Description:
Antagonist activity at prolink-tagged TrkA in human U2OS cells assessed as inhibition of beta-NGF-induced receptor phosphorylation by measuring reduc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50457829
(CHEMBL4208510)
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Copy InChI
Affinity Data
IC50: 5.30E+3nM
Assay Description:
Inhibition of human ERG by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI