Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Patent

US Patent

LigandBDBM435416(US10570116, Compound C24)Copy SMILESCopy InChI

Affinity DataIC50:  12nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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In DepthDetails US Patent
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TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Patent

US Patent

LigandBDBM435416(US10570116, Compound C24)Copy SMILESCopy InChI

Affinity DataIC50:  27nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Merck Patent

US Patent

LigandBDBM435416(US10570116, Compound C24)Copy SMILESCopy InChI

Affinity DataIC50:  3.80E+3nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF® (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI